关节

Recombinant Human Bone Morphogenetic Protein-2: What’s a Spine Surgeon to Do?: Commentary on an article by J. Michielsen, MD, et al.: “The Effect of Recombinant Human Bone Morphogenetic Protein-2 in Single-Level Posterior Lumbar Interbody Arthrodesis”

第一作者：Michael J. Bolesta

2013-05-28 　　我要说

Recombinant human bone morphogenetic protein-2 (rhBMP-2) was approved by the United States Food and Drug Administration in 20021. Many U.S. spine surgeons rapidly embraced this product, more often than not in an off-label fashion, without site-specific data on dosage, safety, or efficacy1. Spinal applications of rhBMP-2 are well attested to in the medical literature. Michielsen et al. make a worthy addition with their article. It is a well-designed and well-executed prospective, randomized, single-blinded study.

关节

Recombinant Human Bone Morphogenetic Protein-2: What’s a Spine Surgeon to Do?: Commentary on an article by J. Michielsen, MD, et al.: “The Effect of Recombinant Human Bone Morphogenetic Protein-2 in Single-Level Posterior Lumbar Interbody Arthrodesis”

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